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Total 115 results found since Jan 2013.

Chronic Respiratory Diseases as a Risk Factor for Herpes Zoster Infection
CONCLUSIONS: In a standard clinical practice setting, the most prevalent respiratory diseases (asthma, COPD and lung cancer) are related to a higher risk of HZ and PHN. These data are fundamental to assess the potential impact of vaccination in this population.PMID:37734964 | DOI:10.1016/j.arbres.2023.08.010
Source: Archivos de Bronconeumologia - September 21, 2023 Category: Respiratory Medicine Authors: Diego Morena Sara Lumbreras Jos é Miguel Rodríguez Carolina Campos Mar ía Castillo Mar ía Benavent Jos é Luis Izquierdo Source Type: research

Oral Nirmatrelvir and Ritonavir for Covid-19 in Vaccinated, Non-Hospitalized Adults, Ages 18-50 Years
CONCLUSION: NMV-r use in vaccinated adults aged 18-50, especially with serious comorbidities, was associated with reduced all-cause hospital visits, hospitalization, and mortality in the first 30 days of Covid-19 illness. However, NMR-r in patients without significant comorbidities or with only asthma/COPD had no association of benefit. Therefore, identifying high-risk patients should be a priority and avoid over-prescription should be avoided.PMID:37387690 | DOI:10.1093/cid/ciad400
Source: Cancer Control - June 30, 2023 Category: Cancer & Oncology Authors: Jeremy Samuel Faust Ashish Kumar Jui Shah Sumanth Khadke Sourbha S Dani Sarju Ganatra Paul E Sax Source Type: research

Epidemiological study of vaccination against SARS-CoV-2 and its impact on COVID-19 progression in a cohort of patients in gran Canaria
Conclusions. Cancer, coronary heart disease, and immunosuppressive treatment were associated with increased COVID-19 mortality. More complete vaccination was associated with lower risk of hospital admission or death. Three doses of the SARS-CoV-2 vaccine were highly associated with the prevention of death and hospital admission in all age groups. These findings suggest that COVID-19 vaccination can help bring the pandemic under control.PMID:37366493 | PMC:PMC10288311 | DOI:10.1016/j.vacun.2023.06.005
Source: Cancer Control - June 27, 2023 Category: Cancer & Oncology Authors: Alejandro de Arriba Fern ández Jos é Luis Alonso Bilbao Alberto Espi ñeira Francés Antonio Cabeza Mora Ángela Gutiérrez Pérez Miguel Ángel Díaz Barreiros Source Type: research

Future perspectives of emerging novel drug targets and immunotherapies to control drug addiction
This article's main highlight is discussing the drug targets of SUDs and their associated mechanisms. Importantly, we have also discussed the scope of prophylactic measures to eliminate drug dependence.PMID:37099943 | DOI:10.1016/j.intimp.2023.110210
Source: International Immunopharmacology - April 26, 2023 Category: Allergy & Immunology Authors: Jonaid Ahmad Malik Javed N Agrewala Source Type: research

The Application of New Approach Methodologies in Respiratory Disease Research: Their Role in Improving Translational Medicine from Bench to Bedside
We describe their potential uses for efficacy and toxicity assessments, to optimise the drug development process and reduce the high failure rates in clinical trials.PMID:37067473 | DOI:10.1177/02611929231170392
Source: Alternatives to Laboratory Animals : ATLA - April 17, 2023 Category: Research Authors: Artur C G da Silva Marize C Valadares Source Type: research

Duration of influenza vaccine effectiveness in the elderly in Japan: A retrospective cohort study using large-scale population-based registry data
CONCLUSIONS: Our study identified moderate vaccine effectiveness in preventing the incidence of influenza in the Japanese elderly. Vaccine effectiveness showed a trend of gradual attenuation. Clinicians should suspect influenza infection even in those vaccinated, especially in elderly individuals who had received vaccination more than 4 or 5 months previously.PMID:37045684 | DOI:10.1016/j.vaccine.2023.03.066
Source: Vaccine - April 12, 2023 Category: Allergy & Immunology Authors: Kohei Uemura Sachiko Ono Nobuaki Michihata Hayato Yamana Hideo Yasunaga Source Type: research

Chronic medical conditions associated with invasive pneumococcal diseases in inpatients in teaching hospitals in S ão Paulo city: Estimating antimicrobial susceptibility and serotype-coverage of pneumococcal vaccines
CONCLUSION: Vaccine with expanded valence of serotypes is necessary to offer broad prevention to IPD. The present data contribute to pneumococcal vaccination public health policies for vulnerable patients, mainly those with comorbidity and the elderly.PMID:36758625 | DOI:10.1016/j.bjid.2023.102746
Source: Braz J Infect Dis - February 9, 2023 Category: Infectious Diseases Authors: Renato A Kfouri Maria-Cristina C Brandileone Marco Aur élio P Sáfadi Rosana Richtmann Alfredo E Gilio Flavia Rossi Thais Guimar ães Ana Luiza Bierrenbach Jos é C Moraes S ão Paulo Study Group for IPD Source Type: research